Table 1.
Study | N | No of prostate cancer deaths |
Total person- years |
Person-years at risk median (min- max) |
Number of SNPs with imputation quality>=0.75 |
---|---|---|---|---|---|
| |||||
PRACTICAL | |||||
CAPS | 412 | 49 | 3 476,6 | 9.3 (0.4–11.8) | 5,752,274Ɨ |
CAPS1 | 492 | 214 | 3 120,2 | 7.1 (0.1–11.8) | 8,933,855$ |
CAPS2 | 1493 | 331 | 11 644,6 | 9.1 (0–11.8) | 8,715,366$ |
CPCS | 925 | 97 | 1 772,1 | 1.3 (0.1–18.1) | 5,550,954Ɨ |
EPIC | 404 | 35 | 467,4 | 0 (0–13.2) | 5,503,395Ɨ |
ESTHER | 300 | 22 | 2 179,9 | 7.7 (0.1–9.8) | 5,495,692Ɨ |
FHCRC | 760 | 46 | 7 716,6 | 8.1 (0.2–18.1) | 5,532,283Ɨ |
MAYO | 737 | 40 | 4 612,8 | 6.8 (0.1–13.9) | 5,555,791Ɨ |
MCCS_PCFS | 1663 | 139 | 41 656,4 | 22.6 (0–71.2) | 5,425,082Ɨ |
MEC | 581 | 15 | 3 531,5 | 5.8 (0.1–13.1) | 5,462,203Ɨ |
PCMUS | 57 | 7 | 68,9 | 1.1 (0.1–4.0) | 5,359,978Ɨ |
SEARCH | 1369 | 70 | 4 966,3 | 3.7 (0.1–4.5) | 5,510,831Ɨ |
STHM1 | 2199 | 71 | 8 247,2 | 3.9 (0–4.3) | 5,724,947Ɨ |
TAMPERE | 2463 | 248 | 21 037,6 | 7.8 (0.8–20.9) | 6,455,082Ɨ |
UKGPCS | 4344 | 826 | 22 906,2 | 4.3 (0–27.3) | 5,485,041Ɨ |
UKGPCS1 | 1783 | 457 | 13 689,0 | 7.0 (0.1–30.0) | 9,536,409Ɣ |
UKGPCS2 | 772 | 189 | 6 961,8 | 9.1 (0–24.9) | 1,235,003Ϯ |
ULM | 365 | 32 | 3 151,9 | 9.0 (0.6–22.0) | 5,457,321Ɨ |
UTAH | 122 | 27 | 603,7 | 4.0 (0.1–26.9) | 5,641,408Ɨ |
| |||||
BPC3 | |||||
ATBC | 245 | 133 | 1 426,2 | 5.8 (0–19.9) | 8,232,459§ |
CPSII | 636 | 79 | 5 859,4 | 9.2 (0.3–16.3) | 7,448,367§ |
EPIC | 431 | 159 | 2 197,3 | 5.2 (0–14.3) | 7,612,553§ |
HPFS | 214 | 37 | 1 616,6 | 7.6 (0.1–14.4) | 7,539,277§ |
MEC | 244 | 23 | 1 868,3 | 7.7 (0.9–15.4) | 7,571,269§ |
PHS | 298 | 97 | 2 811,8 | 9.4 (0–24.7) | 7,569,352§ |
PLCO | 714 | 70 | 4 664,5 | 6.7 (0.1–12.9) | 7,526,690§ |
| |||||
Total | 24023 | 3513 | 182 254,8 | ||
| |||||
CONOR | 1496 | 791 | 8741.4 | 5.0 (0.08–20.8) |
Genotyped on a custum Illumina SNP infimum chip (iCOGS) with 211,155 SNPs, enriched in regions associated with incidence of prostate, breast and ovarian cancer.
Genotyped on Illumina Infinium HumanHap 550 Array.
Genotyped on Illumina iSELECT in 43,671 SNPs.
Genotyped on Affymetrix GeneChip 5.0K or 500K.
Genotyped on Illumina Human 610 or 610K.