Fig. 2. Over-expression of STS attenuates lithocholic acid (LCA)-induced cholestasis.
Both wild-type (WT) and STS transgenic (Tg) mice were given either vehicle (C and D) or LCA (A, B, E and F) via daily gavage for four days. (A and B) Gross appearance of representative livers. (C–F) Liver paraffin sections were histologically examined by hematoxylin and eosin (H&E) staining. Areas marked by asterisks indicate liver necrosis.