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. 2017 Nov 7;12(11):e0185904. doi: 10.1371/journal.pone.0185904

Table 1. Moderate/severe adverse events observed overall and 2 and 7 days post-circumcision among N = 427 HIV-uninfected, sexually-active adult men surgically circumcised within the National Safe Male Circumcision program in Gaborone, Botswana.

2 days post-circumcision (n = 401) 7 days post-circumcision (n = 395) Overall (n = 415)a
Events Participants
with ≥1 event
Rate per 100 circumcisionsb Events Participants
with ≥1 event
Rate per 100 circumcisionsb Events Participants
with ≥1 eventc
Rate per 100 circumcisionsb
Any adverse eventd 10 10 2.5 21 19e 4.8 31 28e 6.7
Hematoma 4 4 1.0 8 8 2.0 12 11 2.7
Bleeding 3 3 0.7 2 2 0.5 5 5 1.2
Infection 2 2 0.5 7 7 1.8 9 9 2.2
Pain 1 1 0.2 3 3 0.7 4 4 1.0
Insufficient skin removed 1 1 0.2 1 1 0.2 2 2 0.5
Delayed healing 0 0 0 3 3 0.7 3 3 0.7

a 415 participants attended one or both follow-up visits at day 2 or day 7.

b Rate per 100 circumcisions calculated by dividing the number of participants assessed at the follow-up by the number of participants with ≥1 event

c Number of unique participants with either ≥1 events at day 2 or day 7.

d Exclusive of pain-related adverse events. Other adverse events assessed, but no events observed included injury to penis, excess skin removed, micturition, and anesthesia-related complications.

e One participant had one event at day 2 and day 7, and two participants had two events each at day 7.