Table 2.

Recently published children’s health cohort study descriptions

Cohort Study Name	Cohort Profile First Author	Study Design	Recruitment and follow-up	Geographic location	Study Aims
The VicGeneration (VicGen) study: An Australian oral health birth cohort. [37]	Johnson S	Birth cohort, 465 mother-child and 1 father-child dyad	Seven waves of data collection have been conducted over 8 years (2008–15)	State of Victoria, Australia	Explore three significant areas of research in child oral health: describing the natural history of caries (decay) from infancy to 5 years; characterization of the salivary microbiota in infants, from 1 month of age through to early childhood, and that of their primary caregiver; and examine the relative contributions of biological, environmental and socio-behavioural factors.
The Norwegian Mother and Child Cohort Study (MoBa). [38]	Magnus P	Pregnancy cohort with a family design; as of Sept 2015, the cohort includes more than 114 000 children, 95 000 mothers and 75 000 fathers	Recruited pregnant mothers and fathers-to-be from 1999 through 2008; Follow-up include questionnaire completion during pregnancy, and when the child was 6 months, 18 months, 3, 5, 7, 8 and 13 years old as well as linkages to health registries.	Norway, includes 50 of Norway’s 52 hospitals with maternity units.	The main aim of MoBa is to detect causes of serious diseases through estimation of specific exposure-outcome associations especially among the children but also among parents.
Hamamatsu Birth Cohort for Mothers and Children (HBC Study). [39]	Takagai S	Birth cohort; 1258 neonates (including 38 twins) from 1138 mothers.	Recruited between November 2007 and March 2011; Follow-up started during pregnancy and continued during infancy at 1, 4, 6, 10, 14, 18, 24, 32, and 40 months, 4.5 years, 6 years and 8 years. Further follow-up visits are also planned.	All but five of the neonates were born at the University Hospital of Hamamatsu University School of Medicine, Japan.	Designed to elucidate the early developmental trajectories of children living in the community in Japan.
The EDEN mother-child cohort on the prenatal and early postnatal determinants of child health and development. [40]	Heude B	Birth cohort; 2002 pregnant women were enrolled in the study (1034 women from Nancy and 968 from Poitiers)	Recruitment extended from 2003 to 2006; followed-up for up to 8 years.	Two university maternity clinics, in Nancy and Poitiers, France	The overall objective was to examine the relations and potential interactions between maternal exposures and health status during pregnancy, fetal development, health status of the infant at birth and the child’s health and development
The Saguenay Youth Study (SYS). [41]	Pausova Z	Two-generational study of adolescents and their parents (n= 1029 adolescents and 962 parents)	Recruitment and assessment took place over a 10-year period (2003–12) and a second follow-up period took place from 2012 and 2015.	Genetic founder population of the Saguenay Lac St Jean region of Quebec, Canada	Investigating the etiology, early stages and trans-generational trajectories of common cardiometabolic and brain diseases. The ultimate goal of this study is to identify effective means for increasing healthy life expectancy.
The Health Outcomes and Measures of the Environment (HOME) study. [42]	Braun JM	Prospective pregnancy and birth cohort; 401 pregnancy women were enrolled.	Recruitment between March 2003 and January 2006; Follow-up during pregnancy and when children were 5 weeks and 1, 2, 3, 4, 5 and 8 years old.	Greater Cincinnati OH metropolitan area	To determine whether early life environmental chemical exposures influence children’s health