Table 4. Association of PD-1, PD-L1, and PD-L2 expression with survival.

Clinical features	Total patients(n)	Deaths(n)	Median OS(95% CI)	P	Progression(n)	Median PFS(95% CI)	P
PD-1, cells/HPF				0.008			0.037
<70	70	12	Not reached		34	24.7 (9.8-39.5)
≥70	6	4	15.8 (11.7-19.9)		6	10.4 (3.3-17.5)
PD-L1, cells/HPF				0.814			0.895
<100	66	14	Not reached		34	17.9 (6.9-28.8)
≥100	10	2	Not reached		6	23.4 (13.1-33.8)
PD-L2, cells/HPF				0.310			0.953
<100	44	8	Not reached		24	23.4 (12.8-33.9)
≥100	32	8	Not reached		16	17.1 (13.9-20.3)

OS, overall survival; PFS, progression-free survival; HR, hazard ratio; CI, confidence interval; HPF, high power field.