Table 1. Summary of clinical information, tumor cell yield and intra-cranial tumor formation of PLGG tumors.
No. | Tumor ID | Age, Gender | Dx, WHO Grade | Tumor cell number(x 106) | Site of injection | Tumor formation in mouse brains | ||
---|---|---|---|---|---|---|---|---|
Total | Injected/mouse | Total | With Tumor | |||||
1 | ST-1267¶ | 1 y, M | PA, I | 1 | 0.1 | ICb | 5 | 0 |
2 | ST-1342¶ | 3 y, F | PA, I | 1.8 | 0.1 | ICb | 2 | 0 |
3 | ST-1610¶ | 15 y, M | PA, I | 1 | 0.1 | ICb | 5 | 0 |
4 | ST-1823 | 11 y, M | PA, I | 0.38 | 0.1 | ICb | 3 | 0 |
5 | ST-1828 | 8 y, M | PA, I | 0.33 | 0.1 | ICb | 3 | 0 |
6 | ST-2076 | 8 y, M | PA, I | 1.05 | 0.1 | ICb | 5 | 0 |
7 | ST-2109* | 4 y, F | PA, I | 2.68 | 0.16 | ICb | 10 | 0 |
8 | ST-2354*¶ | 6 y, M | PA, I | 3.6 | 0.25 | IC | 8 | 0 |
9 | ST-2431* | 4 y, F | PA, I | 0.72 | 0.1 | IC | 5 | 0 |
10 | ST-2446*¶ | 1 y, M | PA, I | 1.76 | 0.085 | ICb | 3 | 0 |
11 | ST-2794*¶ | 5 y, F | PA, I | 1.12 | 0.16 | ICb | 3 | 0 |
12 | ST-2879*¶ | 12y, M | PA, I | 1.1 | 0.1 | ICb | 5 | 0 |
13 | ST-2990¶ | 11 y, F | PA, I | 1.54 | 0.2 | ICb | 5 | 0 |
14 | ST-3016 | 9 y, M | PA, I | 0.45 | 0.12 | ICb | 3 | 0 |
15 | ST-3278* | 10 y, F | PA, I | 2 | 0.15 | ICb | 5 | 0 |
16 | ST-3526*¶ | 9 y, M | PA, I | 4.3 | 0.15 | ICb | 10 | 0 |
17 | ST-3580¶ | 13 y, F | PA, I | 1.12 | 0.2 | ICb | 5 | 0 |
18 | ST-3593 | 5 y, M | PA, I | 1.55 | 0.15 | ICb | 10 | 0 |
19 | ST-3648¶ | 6 y, M | PA, I | 2.7 | 0.28 | IC | 7 | 0 |
20 | ST-4109¶ | 4 y, F | PA, I | 2 | 0.2 | ICb | 5 | 0 |
21 | ST-4666¶ | 1 y, F | PA, I | 1.85 | 0.15 | ICb | 10 | 0 |
22 | ST-1756*¶ | 9 y, M | PA, I | 0.025 | No | |||
23 | ST-2270* | 9 y, M | PA, I | 0.1 | No | |||
24 | ST-2439* | 8 y, M | PA, I | 0.058 | No | |||
25 | ST-2728¶ | 17 y, M | PA, I | 0.03 | No | |||
26 | ST-3490 | 13 y, M | PA, I | 0.01 | No | |||
27 | ST-3510¶ | 10 y, F | PA, I | 0.05 | No | |||
28 | ST-5293¶ | 8 y, F | PA, I | 0.05 | No | |||
29 | ST-5336*¶ | 5 y, M | PA, I | 0.4 | No | |||
30 | ST-4461 | 11 y, F | AST, II | 0.31 | 0.1 | ICb | 3 | 0 |
31 | ST-4388*¶ | 11 y, F | AST, II | 0.03 | No | |||
32 | ST-4034¶ | 6 y, F | GG | 0.06 | No | |||
33 | ST-2829*¶ | 12 y, M | GG | 0.37 | 0.063 | ICb | 5 | 0 |
34 | ST-4524 | 13 y, F | GG | 2.55 | 0.25 | IC | 10 | 0 |
35 | ST-4710¶ | 13 y, F | GG | 0.36 | No | |||
36 | ST-3635* | 10 y, F | PXA, II | 3.48 | 0.1 | IC | 7 | 2 |
Note: *Tested for neurosphere formation, ¶Analyzed with FCM for CSC markers, Dx= diagnosis, ICb=Intra-cerebellar, IC=Intra-cerebral, PA=Pilocytic astrocytoma, AST=astrocytoma, GG=Ganglioglioma, PXA = Pleomorphic Xanthoastrocytoma