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. 2017 Sep 23;8(50):87699–87709. doi: 10.18632/oncotarget.21181

Figure 2. Kaplan–Meier survival curves illustrating prognostic effects of high MCL1 gain in different subgroup of ESCC patients.

Figure 2

(A and B) In patients without lymph node metastasis (n=135), high MCL1 gain tended to associate with better DFS (P=0.090) and OS (P=0.081). (C and D) In patients without lymph node metastasis and with disease free survival time greater than or equal to 12 months (n=120), high MCL1 gain was associated with better DFS (P=0.009) and OS (P=0.014). (E and F) In patients with lymph node metastasis (n=127), high MCL1 gain tended to associate with poorer DFS (P=0.098) and OS (P=0.133). (G and H) In patients with lymph node metastasis and with disease free survival time greater than or equal to 29 months (n=36), high MCL1 gain tended to associate with poorer DFS (P=0.007) and OS (P=0.029). (I and J) In stage I-II patients (n=156), high MCL1 gain tended to associate with better DFS (P=0.142) and OS (P=0.135). (K and L) In stage I-II patients with disease free survival time greater than or equal to 12 months (n=142), high MCL1 gain tended to be associated with better DFS (P=0.046) and OS (P=0.069). (M and N) In stage III-IVa (n=106) patients, high MCL1 gain tended to be associated with poorer DFS (P=0.199) and OS (P=0.206). (O and P) In stage III-IVa patients with disease free survival time greater than or equal to 29 months (n=25), high MCL1 gain tended to associate with poorer DFS (P=0.021) and OS (P=0.068).