Table 2. Univariate and mutivariate survival analysis for disease-free survival and overall survival in full cohort of ESCC.
| DFS | OS | |||
|---|---|---|---|---|
| P value | Hazard ratio (CI 95%) | P value | Hazard ratio (CI 95%) | |
| Univariate analysis | ||||
| Sex | 0.825 | 1.049 (0.684-1.611) | 0.787 | 1.062 (0.686-1.644) |
| Age | 0.412 | 1.145 (0.829-1.583) | 0.366 | 1.163 (0.838-1.615) |
| Grade | 0.137 | 1.272 (0.927-1.747) | 0.204 | 1.232 (0.893-1.701) |
| Invasive Depth | 0.003 | 1.607 (1.174-2.199) | 0.001 | 1.738 (1.251-2.415) |
| Vessel involement | 0.001 | 1.830 (1.266-2.643) | 0.001 | 1.937 (1.333-2.814) |
| Nerve involvement | 0.948 | 0.989 (0.697-1.403) | 0.877 | 0.972 (0.678-1.393) |
| Lymph node metastasis | <0.001 | 3.236 (2.307-4.540) | <0.001 | 3.501 (2.477-4.947) |
| Site | 0.097 | 0.803 (0.620-1.041) | 0.157 | 0.825 (0.633-1.076) |
| Clinical stage | <0.001 | 3.388 (2.447-4.691) | <0.001 | 3.616 (2.597-5.036) |
| Smoking | 0.320 | 1.175 (0.855-1.615) | 0.236 | 1.216 (0.880-1.679) |
| High MCL1 gain | 0.948 | 0.989 (0.697-1.403) | 0.877 | 0.972 (0.678-1.393) |
| Mutivariate analysis | ||||
| Invasive Depth | 0.350 | 1.181 (0.833-1.672) | 0.219 | 1.258 (0.872-1.815) |
| Vessel involement | 0.999 | 1.000 (0.676-1.479) | 0.949 | 1.013 (0.681-1.508) |
| Lymph node metastasis | 0.005 | 2.001 (1.236-3.240) | 0.002 | 2.169 (1.331-3.533) |
| Clinical stage | 0.010 | 1.929 (1.173-3.172) | 0.013 | 1.891 (1.142-3.132) |