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. 2017 Sep 23;8(50):87737–87749. doi: 10.18632/oncotarget.21209

Figure 2. miR-526b inhibits proliferation, migration and invasion of HCC cells.

Figure 2

(A) SMMC-7721 cells that were transfected with miR-526b mimic or negative control (NC) mimic were detected by qRT-PCR for miR-526b expression. n = three repeats with similar results, *P<0.05 by t test. (B) CCK-8 assays revealed that miR-526b silencing inhibited proliferation of SMMC-7721 cells. n = three repeats with similar results, *P<0.05 by ANOVA. (C) Transwell assays confirmed that miR-526b overexpression restrained migration and invasion of SMMC-7721 cells. n = three repeats with similar results, *P<0.05 by t test, respectively. (D) Hep3B cells were transfected with miR-526b inhibitor and negative control (NC) inhibitor, respectively, and measured by qRT-PCR for miR-526b expression. n = three repeats with similar results, *P<0.05 by t test. (E) and (F) upregulating miR-526b expression enhances proliferative, migratory and invasive abilities of Hep3B cells. n = three repeats with similar results, *P<0.05 by ANOVA and t test, respectively.