Figure 3. Protein expression analysis and RASSF1A methylation in metastatic CRC of Group 1.
Different expression levels of membranous (A) and cytoplasmic β-catenin (B), membranous NHERF1 (C), TWIST1 (D), nuclear HIF-1α (E) and RASSF1A methylation levels (F) between T and LM compartments. Black square in each box represents the mean percentage of positive cells. Circle indicates outlier and horizontal line in each box indicates the median. Abbreviation: T, tumor and LM, liver metastasis. ***p < 0.0001; **p < 0.001; *p < 0.05.