Table 3. Genotypic frequencies comparison of the five SNPs among control, CIN and cervical cancer groups.
| SNPs | Genotypes(n, %) | P value | ||||
|---|---|---|---|---|---|---|
| Control VS CIN | CIN VS cervical cancer | Control VS cervical cancer | ||||
| rs11134527 | A/A | A/G | G/G | 0.013 | 0.366 | 0.101 |
| Control | 242(41.5%) | 273(46.8%) | 68(11.7%) | |||
| CIN | 147(36.7%) | 180(45.0%) | 73(18.2%) | |||
| Cervical cancer | 233(36.6%) | 294(48.3%) | 92(15.1%) | |||
| rs74693964 | C/C | C/T | T/T | 0.702 | 0.454 | 0.302 |
| Control | 541(92.8%) | 41(7.0%) | 1(0.2%) | |||
| CIN | 376(94.0%) | 23(5.8%) | 1(0.3%) | |||
| Cervical cancer | 576(94.6%) | 33(5.4%) | 0(0.0%) | |||
| rs6062251 | C/C | C/T | T/T | 0.225 | 0.007 | 0.293 |
| Control | 63(10.8%) | 272(46.7%) | 248(42.5%) | |||
| CIN | 34(8.5%) | 207(51.7%) | 159(39.8%) | |||
| Cervical cancer | 78(12.8%) | 259(42.5%) | 272(44.7%) | |||
| rs531564 | C/C | C/G | G/G | 0.952 | 0.047 | 0.043 |
| Control | 7(1.2%) | 118(20.2%) | 458(78.6%) | |||
| CIN | 4(1.0%) | 80(20.0%) | 316(79.0%) | |||
| Cervical cancer | 17(2.8%) | 144(23.6%) | 448(73.6%) | |||
| rs1834306 | A/A | A/G | G/G | 0.811 | 0.834 | 0.875 |
| Control | 126(21.6%) | 289(49.6%) | 168(28.8%) | |||
| CIN | 91(22.8%) | 190(47.5%) | 119(29.7%) | |||
| Cervical cancer | 139(22.8%) | 299(49.1%) | 171(28.1%) | |||