Table 2. Main results of the meta-analysis.
Categories | Number of datasets | HR | 95%CI | P | Degree of heterogeneity (I2 statistics; %) |
---|---|---|---|---|---|
OS | 19 | 1.48 | 1.19-1.85 | <0.001 | 37.5 |
Study quality | |||||
Score ≥ 7 | 10 | 1.24 | 0.93-1.65 | 0.136 | 44.3 |
< 7 | 9 | 2.04 | 1.53-2.71 | <0.001 | 0 |
Sample size | |||||
≥ 100 | 6 | 1.44 | 0.98-2.13 | 0.065 | 74.3 |
< 100 | 13 | 1.57 | 1.19-2.07 | 0.001 | 0 |
Duration of follow-up (Months) | |||||
> 36 | 9 | 1.42 | 1.04-1.95 | 0.029 | 48.7 |
≤ 36 | 10 | 1.56 | 1.11-2.20 | 0.01 | 31.2 |
Histology types | |||||
All | 13 | 1.49 | 1.06-2.09 | 0.021 | 50.9 |
Serous | 6 | 1.52 | 1.22-1.88 | <0.001 | 0 |
Region | |||||
European | 12 | 1.44 | 1.07-1.95 | 0.016 | 48.3 |
North American | 3 | 1.25 | 0.69-2.26 | 0.456 | 33.8 |
Asian | 4 | 1.95 | 1.29-2.95 | 0.002 | 0 |
Analysis type | |||||
Multivariate | 8 | 1.52 | 1.01-2.28 | 0.044 | 68.2 |
Univariate | 11 | 1.49 | 1.21-1.84 | <0.001 | 0 |
HR: hazard ratio; CI: confidence interval; OS: overall survival.