Table 1.
Intravitreal Injections in NHPs Indicating the Primate Number, Vector Used, Dose, and Time after Injection
| NHP No. | Eye | AAV Vector | Dose (vg/eye) | Age (Years) | Euthanasia (Months) |
|---|---|---|---|---|---|
| 1 | right | AAV2-SNCG-CatCh-GFP | 1 × 1011 | 10 | 3 |
| left | AAV2-SNCG-CatCh-GFP | 5 × 1011 | |||
| 2 | right | AAV2-SNCG-CatCh | 5 × 1011 | 8 | 3 |
| left | AAV2-SNCG-CatCh | 5 × 1011 | |||
| 3 | right | AAV2-SNCG-CatCh | 5 × 1011 | 8 | 3 |
| left | AAV2-SNCG-CatCh | 5 × 1011 | |||
| 4 | right | AAV2-SNCG-CatCh | 1 × 1011 | 4 | 4 |
| left | AAV2-SNCG-CatCh | 1 × 1011 | |||
| 5 | right | AAV2-SNCG-CatCh | 1 × 1011 | 4 | 6 |
| left | AAV2-SNCG-CatCh | 1 × 1011 | |||
| 6 | right | AAV2-CMV-CatCh | 1 × 1012 | 9 | 6 |
| left | AAV2-CMV-CatCh | 1 × 1012 | |||
| 7 | right | AAV2-SNCG-CatCh | 1 × 1012 | 8 | 6 |
| left | AAV2-SNCG-CatCh | 1 × 1012 | |||
| 8 | right | AAV2-SNCG-CatCh | 5 × 1011 | 6 | 6 |
| left | AAV2-SNCG-CatCh | 5 × 1011 | |||
| 9 | right | AAV2-SNCG-CatCh | 5 × 1011 | 16 | 4.5 |
| left | AAV2-CMV-CatCh | 5 × 1011 | |||
| 10 | right | AAV2-CMV-CatCh | 5 × 1011 | 6 | 6 |
| left | AAV2-CMV-CatCh | 5 × 1011 |