Table 1.
NHP No. | Eye | AAV Vector | Dose (vg/eye) | Age (Years) | Euthanasia (Months) |
---|---|---|---|---|---|
1 | right | AAV2-SNCG-CatCh-GFP | 1 × 1011 | 10 | 3 |
left | AAV2-SNCG-CatCh-GFP | 5 × 1011 | |||
2 | right | AAV2-SNCG-CatCh | 5 × 1011 | 8 | 3 |
left | AAV2-SNCG-CatCh | 5 × 1011 | |||
3 | right | AAV2-SNCG-CatCh | 5 × 1011 | 8 | 3 |
left | AAV2-SNCG-CatCh | 5 × 1011 | |||
4 | right | AAV2-SNCG-CatCh | 1 × 1011 | 4 | 4 |
left | AAV2-SNCG-CatCh | 1 × 1011 | |||
5 | right | AAV2-SNCG-CatCh | 1 × 1011 | 4 | 6 |
left | AAV2-SNCG-CatCh | 1 × 1011 | |||
6 | right | AAV2-CMV-CatCh | 1 × 1012 | 9 | 6 |
left | AAV2-CMV-CatCh | 1 × 1012 | |||
7 | right | AAV2-SNCG-CatCh | 1 × 1012 | 8 | 6 |
left | AAV2-SNCG-CatCh | 1 × 1012 | |||
8 | right | AAV2-SNCG-CatCh | 5 × 1011 | 6 | 6 |
left | AAV2-SNCG-CatCh | 5 × 1011 | |||
9 | right | AAV2-SNCG-CatCh | 5 × 1011 | 16 | 4.5 |
left | AAV2-CMV-CatCh | 5 × 1011 | |||
10 | right | AAV2-CMV-CatCh | 5 × 1011 | 6 | 6 |
left | AAV2-CMV-CatCh | 5 × 1011 |