Table 4.
Genetic and environmental influences on the association between AAU and theta-band dynamics
| AAU | Theta-band Phenotype | Model-implied correlations | Proportion (%) of rP due to |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Phenotype 1 – Phenotype 2 | r | A | E | A | E | rP | rG | rE | A | E |
| AAU – MFC Power Incongruent | −.12 | .80 (.75, .84) |
.20 (.16, .25) |
.60 (.51, .67) |
.40 (.33, .49) |
−.12 (−.20, −.04) |
−.16 (−.28, −.04) |
−.02 (−.15, .12) |
96 | 4 |
| AAU – MFC-dPFC FC Incongruent | −.13 | .80 (.75, .84) |
.20 (.16, .25) |
.39 (.28, .50) |
.61 (.50, .72) |
−.12 (−.20, −.05) |
−.1 7 (−.33, −.02) |
−.08 (−.21, .06) |
79 | 21 |
Notes: Parameter estimates from the separate bivariate AE models between AAU and each theta-band EEG measure. Abbreviations: AAU = adolescent alcohol use; MFC = medial frontal cortex; dPFC = dorsal prefrontal cortex; FC = functional connectivity; r = observed phenotypic correlation; A = additive genetic effects with 95% confidence intervals (CIs); E = nonshared environmental effects; rP = model-implied phenotypic correlation; rG = genetic correlation; rE = nonshared environmental correlation.