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A. NMDA/AMPA ratios evoked by corticostriatal (left) and thalamostriatal (right) stimulation. Peak amplitude of the NMDAR-mediated current was divided by the amplitude of the AMPAR-mediated current evoked by corticostriatal or thalamostriatal stimulation for each neuron, and then averaged across neurons. B. NMDA/AMPA ratios of currents evoked by corticostriatal stimulation compared to those evoked by thalamostriatal stimulation in MSNs from WT (left) and R6/2 (right).
