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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Neurobiol Dis. 2017 Jul 27;108:29–44. doi: 10.1016/j.nbd.2017.07.020

Fig. 9.

Fig. 9

VGLUT1/VGLUT2 terminal input onto D2R-labeled spines (D2-SP) within the dorsolateral striatum. Electron photomicrographs showing single DAB labeling for D2R only within spines (panels a and b, WT and R6/2, respectively), VGLUT1 (panels c and d) and VGLUT2 (panels e and f) labeling within nerve terminals (NT), along with nerve terminal glutamate immuno-gold labeling (arrowhead within the nerve terminal). Synaptic contacts (arrows) are illustrated. White asterisk shows DAB label, black or white arrows indicate synapse, arrowheads indicate gold particle, NT is the nerve terminal, while SP is the spine. a: D2R-labeled spine, WT; b: D2R-labeled spine, R6/2; c: D2R-labeled spine and VGLUT1 labeled terminal, WT; d: D2R-labeled spine and VGLUT1 labeled terminal, R6/2; e: D2R-labeled spine and VGLUT2 labeled terminal, WT; f: D2R-labeled spine and VGLUT2 labeled terminal, R6/2. Calibration bar: 500 nm.