Table 6.

Region of Interest Analysis

Study	How ROI was defined	Statistical test used on ROI	Significance threshold
Allan et al.	Brodmann areas were defined by WFU_pickatlas, auditory nuclei were defined via MNI coordinates	Two sample t-test
Boyen et al.	Brodmann areas were defined by WFU_pickatlas, auditory nuclei were defined via MNI coordinates, left and right cerebellum defined according to the WFU_pickatlas	ANCOVA regression model and then two sample t-test	P<0.05 corrected for FDR for cluster
Husain et al.	Brodmann areas were defined by WFU_pickatlas, auditory nuclei were defined via MNI coordinates	ANOVA regression model and then two sample t-test	P<0.005 uncorrected at cluster level for one test. Also did second test with P<0.001 uncorrected and P<0.05 for voxel and cluster level
Landgrebe et al.	Brodmann areas were defined by WFU_pickatlas, auditory nuclei were defined via MNI coordinates	Voxelwise t-tests	P<0.05 FDR corrected for voxel and cluster level
Leaver et al. (2011)	Auditory cortex was defined by a silence vs. sound contrast. MGN was defined by WFU_pickatlas	Two sample t-test	p<0.0001 uncorrected for voxel level *For superior temporal cortex p<0.01
Leaver et al. (2012)	ROIs were defined by MNI coordinates and by prior templates with manually identified structures	Two sample t-test
Melcher et al.	Auditory nuclei were defined by MNI coordinates	Two sample t-test	P<0.001 uncorrected for cluster level and P<.05 unclear correction for cluster level
Mühlau et al.	Brodmann areas were defined by WFU_pickatlas, auditory nuclei were defined via MNI coordinates	Voxelwise t-tests	P<0.05 FDR correction at voxel and cluster level
Vanneste et al.	Brodmann areas were defined by WFU_pickatlas	Split-half analysis and then 3 simple regression analyses	P<0 .001 uncorrected and p <0.05 FDR correction at voxel and cluster level