Table 1.
Participants’ demographics, single-nucleotide polymorphisms, and neuropsychological measures.
| Age (yr) | Gender | Race | Ethnicity | Education* (yr) | BDNF † | APOE † | MMSE | Abbreviated Stanford-Binet IQ | Verbal KN | Nonverbal FR | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Participant 01 | 24 | M | Asian | non-Hispanic | 16 | Val/Met | ε3/ε3 | 30 | 100 | 10 | 10 |
| Participant 02 | 26 | M | Other | non-Hispanic | 19 | Val/Val | ε3/ε4 | 30 | 121 | 17 | 10 |
| Participant 03 | 23 | M | Multiracial | Hispanic | 16 | Val/Val | ε3/ε3 | 30 | 106 | 11 | 11 |
| Participant 04 | 56 | F | African-American | non-Hispanic | 14 | - | - | 30 | 97 | 9 | 10 |
| Participant 05 | 47 | M | White | non-Hispanic | 20+ | Val/Val | ε3/ε3 | 30 | 133 | 17 | 14 |
| Participant 06 | 21 | M | Asian | non-Hispanic | 16 | - | - | 30 | 94 | 8 | 10 |
| Participant 07 | 53 | M | White | non-Hispanic | 16 | Val/Val | ε3/ε4 | 30 | 106 | 13 | 9 |
| Participant 08 | 51 | M | White | non-Hispanic | 16 | Val/Val | ε3/ε3 | 30 | 115 | 14 | 11 |
| Participant 09 | 62 | M | White | non-Hispanic | 16 | Val/Met | ε3/ε4 | 30 | 118 | 12 | 14 |
| Participant 10 | 21 | M | White | Hispanic | 15 | Val/Val | ε3/ε4 | 30 | 109 | 14 | 9 |
| Participant 11 | 22 | M | White | Hispanic | 17 | Val/Val | ε2/ε3 | 30 | 112 | 10 | 14 |
| Participant 12 | 32 | M | White | non-Hispanic | 19 | Val/Val | ε3/ε3 | 29 | 100 | 9 | 11 |
| Participant 13 | 28 | M | White | Hispanic | - | Val/Val | ε3/ε3 | 30 | 115 | 13 | 12 |
| Participant 14 | 50 | F | African-American | non-Hispanic | 12 | - | - | 30 | 97 | 10 | 9 |
| Participant 15 | 23 | M | White | non-Hispanic | 17 | Val/Val | ε2/ε3 | 30 | 127 | 16 | 13 |
| Participant 16 | 24 | M | Multiracial | Hispanic | 17 | Val/Met | ε2/ε3 | 28 | 115 | 12 | 13 |
| Participant 17 | 22 | M | Asian | non-Hispanic | 17 | Val/Met | ε3/ε4 | 30 | 103 | 9 | 12 |
| Participant 18 | 47 | M | African-American | non-Hispanic | 18 | Val/Met | ε3/ε3 | 30 | 88 | 9 | 7 |
| Participant 19 | 32 | M | Asian | non-Hispanic | 20+ | Val/Met | ε3/ε4 | 30 | 103 | 8 | 13 |
| Participant 20 | 65 | M | Asian | non-Hispanic | 20+ | Val/Val | ε3/ε4 | 30 | 124 | 15 | 13 |
| Participant 21 | 46 | M | White | non-Hispanic | 13 | Val/Val | ε3/ε4 | 30 | 88 | 9 | 7 |
All participants were right-handed. APOE, apolipoprotein E; BDNF, brain-derived neurotrophic factor; FR, fluid reasoning; IQ, intelligence quotient; KN, knowledge; MMSE, Mini-Mental State Examination. Racial and ethnic categories were defined based on the National Institutes of Health policy and guidelines on the inclusion of women and minorities as subjects in clinical research (NIH Office of Extramural Research, 2001).
*
Education data were available for 20 participants.
†
BDNF and APOE data were available for 18 participants.