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. Author manuscript; available in PMC: 2018 Nov 15.
Published in final edited form as: J Immunol. 2017 Oct 9;199(10):3437–3452. doi: 10.4049/jimmunol.1700953

Figure 8. Precursor frequencies of Gag293-specific clonotypes.

Figure 8

(A) The percentage of ADVAX-induced Gag293-specific clonotypes was computed in healthy donor clonotypic repertoires obtained from total T cells. Left: % found in a dataset of 541,401 TRA clonotypes and 693,571 TRB clonotypes from healthy donors (HD) (40); Right: % found in a dataset of 4,406 TRA public clonotypes and 3,101 TRB public clonotypes from healthy donors (HD) (41); The percentage of TRAV29 (white bar), TRAV24 (black bar), and TRBV2 (grey bar) Gag293-specific clonotypes found at least once in the HD repertoires is reported.

(B to D) Frequency of the TRAV24 (B), TRAV29 (C), and TRBV2 (D) Gag293-specific clonotypes found within the dataset of 541,401 TRA clonotypes and 693,571 TRB clonotypes from healthy donors (HD) reported by J. heather et al (40). Dotted lines mark the 10−5 frequency threshold. Public clonotypes are marked with an asterisk (*).