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Sex‐specific regulation of mTORC2 substrates is mediated by gonadal hormones. Data from intact individuals are replicated from Figs 1 and 3, and shown here for ease of comparison. Results from samples collected from 12‐month‐old mice, n = 6 per group. P‐values were calculated using a Student's t‐test; see Table 1 for additional details. * represents P < 0.05; ** represents P < 0.01; *** represents P < 0.005.
