Table 1.
Clinical data of the study participants
| Premenopausal n = 6 | Postmenopausal nonusers n = 9 | Postmenopausal HRT users n = 9 | |
|---|---|---|---|
| Age (years) | 31.8 ± 1.8 | 57.3 ± 2.2 | 57.3 ± 2.2 |
| Health and lifestyle variables | |||
| Number of chronic diseases or conditions | |||
| Allergy (n) | 4 | 2 | 1 |
| Musculoskeletal problems (n) | 4 | 4 | 3 |
| Migraine (n) | 3 | 1 | 0 |
| Cancer history (n) | 0 | 1 | 0 |
| Hypertension with medication (n) | 0 | 4 | 5 |
| Current smokers (n) | 2 | 1 | 1 |
| Physical activity | |||
| Sedentary (n) | 0 | 1 | 1 |
| Moderately active (n) | 3 | 3 | 3 |
| Active (n) | 3 | 5 | 4 |
| Gynecological data | |||
| Age at first menstruation (years) | 13.3 ± 2.0 | 12.9 ± 1.4 | 12.6 ± 1.0 |
| Age at last menstruation (years) | Still menstruating | 48.7 ± 4.2 | 50.7 ± 2.0 |
| Number of participants with regular menstrual cycle (n) | 6 | No cycle | No cycle |
| Mean length of the cycle (days) | 28.3 | ||
| Number of participants been pregnant (n) | 4 | 8 | 7 |
| Number of pregnancies per participant (n) | 0–3 | 0–3 | 0–3 |
| Number of participants having used hormonal contraceptive during past 10 years; but not within last 5 years (n) | 3 | 1 | 1 |
| Number of participants with ovariectomy and/or hysterectomy (n) | 0 | 1 | 3 |
| Number of participants reporting menopausal symptoms | 0 | 9 | 7 |
| Use of HRT | Never | Never | Currently |
| Duration of HRT use (years) | 7.3 ± 3.3 | ||
| Number of E2‐HRT users (n) | 3 | ||
| Number of E2+progestogen‐HRT users (n) | 3 | ||
| Number of Tib‐HRT users | 3 | ||
Data are presented either as mean ± standard deviation or as total number of participants. HRT = hormone replacement therapy, E2 = 17β‐estradiol, Tib = tibolone.