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. 2017 Oct 2;16(6):1369–1380. doi: 10.1111/acel.12680

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© 2017 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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C/ebpβ is involved in the regulation of Nfe2l2, Sod1, and Hmox1 expression in the MSCs. (A) Putative C/ebpβ binding regions on the Nfe2l2, Sod1, and Hmox1 genes. Red bars show transcription start regions. (B) ChIP‐PCR analysis with the C/ebpβ antibody for the Nfe2l2, Sod1, and Hmox1 promoters. (C) C/ebpβ expression in the MSCs transfected with mmu‐miR‐155 overexpression plasmid (n = 3). Control means the MSCs transfected with the control plasmid containing a scrambled sequence. Asterisk represents significant differences (P < 0.05) compared with control. (D) qPCR for Nfe2l2, Sod1, and Hmox1 in the MSCs transfected with the C/ebp β overexpression plasmid. Asterisks represent significant differences (P < 0.05) compared with control.