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. 2017 Sep 21;16(6):1425–1429. doi: 10.1111/acel.12658

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© 2017 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Examples of different types of interactions between genotype, temperature, and lifespan. (A–F) show survival curves and combined graphs plotting median lifespan vs temperature at 15°, 20°, and 25° for daf‐2 (RNAi), rhy‐1(ok1402), daf‐16(mu86), rsks‐1(ok1255), cep‐1(gk138), and cah‐4 (RNAi) compared to wild‐type (N2). Note that because they are developmentally delayed, rhy‐1 lifespans are shown from L4. All lifespans are available in Figs. S1–S3 (Supporting Information). Significant (P < .05) differences between control and experimental conditions denoted with asterisks (*).