Figure 2.

Sirt2 ^−/− mice exhibit locomotor deficits at 13 months of age. (A) Plotted are the ratios between the time length of the shocks (time that mice stay on the electrified grid) and the number of shocks received, over the duration of each test and (B) bar‐cross test in WT and Sirt2 ^−/− mice at 3.5 and 13 months of age (n = 20/genotype). No falls were recorded. Data represent mean ± SD. Statistical analysis was carried out with Student's t‐test (*P ≤ 0.05, **P ≤ 0.01).