Figure 1.

Power as a function of sample size for different genotype risk ratios. The graphs show the power as a function of sample size for case-control study design assuming multiplicative mode of inheritance with genotype risk ratio (λ) = 3, 2.5, and 2, respectively. Power is computed using the function PowerDiscreteGRR() with the admixture proportion $\theta$ = 0.8, risk allele frequencies $p_x=0.1$ and $p_y=0.4$ for a one-sided test, and adjusted type-I error rate = 0.000025. GRR, genotype risk ratio.