Figure 5.

Inference of α (proportion of beneficial substitutions), ϵ (rate of ancestral error), and DFE parameters: $S_d$ (mean selection coefficient of deleterious mutations), b (shape of distribution of deleterious DFE), $p_b$ (proportion of beneficial mutations), and $S_b$ (mean selection coefficient of beneficial mutations). The figure shows the inference quality for three simulated DFEs (Table 1) with different α values. The DFEs differ only in the simulated value of $S_d.$ A full DFE is inferred from both polymorphism and divergence data, and ϵ is set to zero and is not estimated, or is estimated. The data were simulated with $\mathit{ϵ}=\mathrm{0.05.}$