Table 1. Simulated DFEs.
DFE type | DFE abbreviation | b | α | ||||
---|---|---|---|---|---|---|---|
Full DFEs | Low α, low | LALSD | −10 | 0.4 | 0.02 | 4 | 0.21 |
Low α, low b | LALB | −400 | 0.15 | 0.02 | 4 | 0.21 | |
Low α, low | LALPB | −400 | 0.4 | 0.005 | 4 | 0.21 | |
Low α, low | LALSB | −400 | 0.4 | 0.02 | 0.1 | 0.22 | |
Medium α, medium | MAMSD | −400 | 0.4 | 0.02 | 4 | 0.53 | |
Medium α, low | MALPB | −400 | 0.65 | 0.005 | 4 | 0.50 | |
Medium α, low | MALSB | −400 | 0.4 | 0.07 | 0.1 | 0.50 | |
Medium α, high | MAHSB | −400 | 0.4 | 0.005 | 16 | 0.51 | |
High α, high | HAHSD | −10,000 | 0.4 | 0.02 | 4 | 0.80 | |
High α, high b | HAHB | −400 | 0.65 | 0.02 | 4 | 0.80 | |
High α, high | HAHPB | −400 | 0.4 | 0.07 | 4 | 0.81 | |
High α, high | HAHSB | −400 | 0.4 | 0.02 | 16 | 0.81 | |
High | HSB | −400 | 0.4 | 0.02 | 800 | 0.99 | |
Deleterious DFEs | Low | DelLSD | −10 | 0.4 | 0 | — | 0 |
Low b | DelLB | −400 | 0.15 | 0 | — | 0 | |
Medium | DelMSD | −400 | 0.4 | 0 | — | 0 | |
High | DelHSD | −10,000 | 0.4 | 0 | — | 0 | |
High b | DelHB | −400 | 0.65 | 0 | — | 0 |
The DFE consists of a mixture between gamma and exponential distributions: a new mutation is deleterious with probability and has a selection coefficient drawn from a reflected gamma distribution with mean and shape b; a new mutation is beneficial with probability and has a selection coefficient drawn from an exponential distribution with mean