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. 2017 Sep 22;207(3):949–959. doi: 10.1534/genetics.117.300317

Figure 3.

Figure 3

Effects of telomere capping genes in the BARTL assay. Dicentric chromosome formation was induced in the developing eyes of males carrying the DcY(H1), y+ BS chromosome, using eyGal4 UASFLP (C–I) or eyFLP (J and K), and eye sizes were measured for each genotype. (A and B) Wild-type and BS controls, respectively. (C) The effect of DcY(H1) dicentric production. The eyes are larger than in B, owing to survival and differentiation of some cells that lost BS. The effect of hiphop (D–F), ms(3)K81 (G), and cav (H and I) overexpression. P values are for comparison with C. (J and K) Eye size when FLP is expressed from eyFLP transgene (J), and when Su(var)205 (encoding HP1) is also overexpressed with an early developmental heat shock (K). Typical phenotypes are shown below [i.e., (C′) eyGal4, (E′) UAS-hiphop, (G′) UAS-K81, and (I′) UAS-cav#3]. The numbers of eyes measured for each genotype (A–K) were 20, 43, 110, 35, 16, 16, 14, 18, 18, 30, and 30, respectively. The plots show 5th, 25th, median, 75th, and 95th percentiles.