Table 2.
Authors/[biblio] | Gestational age (weeks) | Maternal age (years) | Known risk factors | Prepartum complications | Clinical signs | Laboratory work up | HPS etiology | Study year |
---|---|---|---|---|---|---|---|---|
Gill et al. 11 | 18 | 30 | No | Non | Fever, hepatomegaly | Pancytopenia, cytolysis | Unclear | 1994 |
Mihara et al. 10 | 16 | 32 | No | Non | Fever | Pancytopenia, hyperferritinemia, markedly elevated LDH | EBV | 1999 |
Nakabayashi et al. 13 | 21 | ND | No | Preeclampsia, DIVC, IUGR | Fever | Thrombopenia, leukopenia, cytolysis | Unclear | 1999 |
Chmait et al. 9 | 29 | 24 | No | DIVC | Adenopathy, fever | Pancytopenia, cytolysis | EBV (postmortem diagnosis) | 2000 |
Yamagushi et al. 17 | 2nd trimester | ND | No | No | Fever, skin lesions | Pancytopenia, hypertriglycemia, hyperferritinemia, cytolysis | HSV | 2005 |
Pérard et al. 12 | 22 | 28 | Lupus | Preeclampsia | Fever | Pancytopenia, hypertriglycemia, hyperferritinemia | Lupus | 2007 |
Hahaoka et al. 27 | 23 | 33 | No | Lymphoma diagnosed | Fever, hepatosplenomegaly | Pancytopenia | B‐cell Lymphoma | 2007 |
Teng et al. 8 | 23 | 28 | No | Transfusion for anemia compensation and dyspnea improvement | Fever, hepatosplenomegaly | Anemia, thrombopenia, hypertriglycemia | Autoimmune hemolytic anemia | 2009 |
Shukla et al. 28 | 23 | 10 | No | No | Fever, hepatosplenomegaly | Pancytopenia, hypertriglycemia, hyperferritinemia | Unclear | 2011 |
Arewa et al. 16 | 21 | 31 | No | No | Fever, jaundice, abdominal pain | Pancytopenia | HIV | 2011 |
Hannebicque Montaigne et al. 5 | 29 | 21 | Mixed connectivitis (lupus, cryoglobulinemia, Gougerot–Sjogren) | ICU transfer at 22 GA due to vascular failure, bilateral PE, at 25 GA | Fever | Pancytopenia, hyperferritinemia, hypertriglycemia | Lupus | 2012 |
Dunn et al. 14 | 19 | 41 | Still disease | No | Fever, skin lesions | Cytolysis, anemia, leukopenia, hypertriglycemia, hyperferritinemia | Still Disease | 2012 |
Mayama et al. 19 | 21 | 28 | No | No | Fever | Pancytopenia hyperferritinemia | Parvovirus B 19 | 2014 |
Tumian et al. 15 | 38 | 35 | No | No | Jaundice | Anemia, thrombopenia, hypertriglycemia, cytolysis | CMV (postmortem diagnosis) | 2015 |
Samra et al. 18 | 16 | 36 | No | No | Fever, hepatosplenomegaly | Pancytopenia, hyperferritinemia | Unclear | 2015 |
Current | 30 | 44 | Raynaud syndrome | Autoimmune | Fever, hepatomegaly | Pancytopenia, hyperferritinemia et hypertriglycemia, cytolysis | History of autoimmune disease | 2015 |
ND, Not documented; IUGR, intrauterine growth retardation; DIVC, disseminated intravascular coagulation; PE, pulmonary embolism; GA, gestational age; CMV, cytomegalovirus; HSV, herpes simplex virus; HIV, human immunodeficiency virus; ICU, intensive care unit; EBV, Epstein–Barr virus.