Table 1.
Description of Methods for calculating allostatic load
| Seeman et al. | Crimmins et al. | ICMH | |
|---|---|---|---|
|
|
|||
| N of Component Measures |
10 | 12 | 10 |
| Itemized Component Measures | Creatinine Clearance | Creatinine Clearance | eGFR |
| Albumin (Serum) | Albumin (Serum) | Albumin (Serum) | |
| BMI | BMI | BMI | |
| SBP | SBP | MAP | |
| DBP | DBP | -- | |
| HbA1c | HbA1c | HbA1c | |
| -- | Fasting blood glucose | -- | |
| Total Cholesterol | Total Cholesterol | Total cholesterol | |
| -- | HDL | HDL | |
| -- | -- | LDL | |
| Triglycerides | Triglycerides | Triglycerides | |
| C-reactive protein | C-reactive protein | -- | |
| Homocysteine | Homocysteine | -- | |
| --- | --- | Urine albumin/creatinine ratio | |
|
| |||
| Scoring Rules | 1 point for each measure exceeding an adverse (high or low) threshold established using NHANES distributions | 1 point for each measure (*) exceeding and adverse (high or low) threshold established using either clinical criteria (e.g. BP) or NHANES distributions | Each measure standardized to a mean of 0 and std. deviation of 1 in each year (**). |
| Standard deviations beyond ± 4 recoded to ± 4. | |||
| Standardized [0, 1] values recoded to [50, 12.5] | |||
| Z-score Method 1: standardizes to the total sample average. | |||