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Volcano plots depicting global gene expression (grey) as well as expression of selected ErbB genes (red dots) that are heavily influenced by EGFR and Hedgehog pathway genes (green dots). Good (left) and poor (right) outcomes are separated. Relative expression is depicted for the comparisons on the left. In good outcomes, ErbB genes (red) and HhP genes (green) are suppressed (shifted right to left) following cetuximab and IPI-926 treatment, respectively.
