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. Author manuscript; available in PMC: 2017 Nov 8.
Published in final edited form as: ACS Chem Biol. 2017 Aug 29;12(9):2436–2447. doi: 10.1021/acschembio.7b00527

Figure 2. Structure Activity Relationship (SAR) study using cScore, EC50 and zebrafish phenotypic screen.

Figure 2

Three validated hits in the zebrafish assay [SJ000291942 (1), SJ000063181 (2), and SJ00037178 (3)] exhibited well-behaved dose-response curves class (‘Sigmoidal’) in the cell-based assay by cScore.