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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Lancet Gastroenterol Hepatol. 2017 May 11;2(7):479–493. doi: 10.1016/S2468-1253(17)30110-3

Figure 4. Activation of T cells.

Figure 4

The presence and functional responsiveness of circulating T cells specific for epitopes in Nexvax2 was tested by ex vivo whole blood interferon(IFN)-γ release assay (IGRA). Fold increase in IFNγ release (stimulation index) stimulated by Nexvax2 peptides compared to medium is shown for participants in the 16-dose study receiving Nexvax2 150µg in the 1st cohort (n=8) (A), and in the 3rd (biopsy) cohort that did not have screening gluten challenge (n=7) (B); median with interquartile range are shown.