Table 1.

Distribution and characteristics of tertiary lymphoid structures in a representative test cohort of bladder tumours

	Overall	Non-muscle invasive low	Muscle invasive high
		grade (NMIBC) TaLG	grade (MIBC) T2HG
Number of patients	N = 28	N = 12	N = 16
Median Age (Range)	68.5 (54–82)	71 (54–80)	66.5 (54–82)
Presence of TLS identifiable by H&E	11 (39%)	1 (8%)	10 (62%)
Presence of TLS identifiable by IHC	15 (54%)	3 (25%)	12 (75%)
Presence of B-cell clusters that do	22 (79%)	9 (75%)	13 (81%)
not qualify as TLS
Concurrent carcinoma in situ	6 (21%)	0 (0%)	6 (38%)
in the TURBT specimen
Lymphovascular invasion	0	0	0