Table 4.
The co-localization pattern of PV+ neurons with ERα, ERβ and AR in the amygdala of the guinea pig in male and female subjects
| Parvalbumin | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ERα | ERβ | AR | |||||||
| PV+ | PV+/ERα+ | % | PV+ | PV+/ERβ+ | % | PV+ | PV+/AR | % | |
| LA | |||||||||
| ♂ | 619.3 ± 51.2 | 4.1 ± 0.4 | 0.66 ± 0.05 | 662.4 ± 32.3 | 92.3 ± 6.9 | 13.93 ± 0.81 | 628.3 ± 39.6 | 0 | – |
| ♀ | 675.6 ± 39.1 | 3.3 ± 0.3 | 0.49 ± 0.07 | 746.5 ± 47.9* | 127.8 ± 9.8** | 17.12 ± 1.42** | 694.8 ± 53.5 | 0 | – |
| BL | |||||||||
| ♂ | 446.2 ± 27.9 | 0 | – | 467.2 ± 42.7 | 32.1 ± 2.2 | 6.87 ± 0.54 | 484.2 ± 35.8 | 0 | – |
| ♀ | 499.3 ± 40.8 | 0 | – | 522.8 ± 29.9 | 29.5 ± 2.6 | 5.65 ± 0.47* | 537.1 ± 33.1 | 0 | – |
| BM | |||||||||
| ♂ | 278.9 ± 19.7 | 2.6 ± 0.3 | 0.92 ± 0.17 | 304.8 ± 23.1 | 88.7 ± 6.3 | 29.15 ± 2.52 | 316.8 ± 24.0 | 2.6 ± 0.3 | 0.81 ± 0.09 |
| ♀ | 301.3 ± 18.6 | 3.1 ± 0.4 | 1.02 ± 0.23 | 346.6 ± 15.7* | 109.3 ± 7.5** | 31.54 ± 1.87 | 332.4 ± 19.1 | 1.2 ± 0.1 | 0.34 ± 0.05 |
| CE | |||||||||
| ♂ | 9.3 ± 0.3 | 0 | – | 9.6 ± 0.8 | 0 | – | 11.2 ± 1.4 | 0 | – |
| ♀ | 7.1 ± 0.5 | 0 | – | 8.7 ± 0.7 | 0 | – | 6.1 ± 0.6 | 0 | – |
| ME | |||||||||
| ♂ | 15.2 ± 0.8 | 0 | – | 16.8 ± 1.3 | 0 | – | 13.3 ± 0.8 | 0 | – |
| ♀ | 13.5 ± 0.9 | 0 | – | 15.5 ± 1.1 | 0 | – | 10.6 ± 0.5 | 0 | – |
| CO | |||||||||
| ♂ | 237.4 ± 10.2 | 2.4 ± 0.2 | 1.03 ± 0.15 | 250.4 ± 19.8 | 65.4 ± 3.4 | 26.12 ± 1.27 | 268.1 ± 14.3 | 2.9 ± 0.2 | 1.07 ± 0.08 |
| ♀ | 225.2 ± 11.6 | 1.2 ± 0.1 | 0.53 ± 0.06 | 219.6 ± 15.9* | 56.2 ± 3.8* | 25.61 ± 1.43 | 241.9 ± 17.6 | 1.8 ± 0.1 | 0.76 ± 0.04 |
Note in both sexes extensive co-localization of PV+ neurons with ERβ and the lack of associations of these cells with ERα or AR. Data were expressed as mean ± standard deviation (SD). As PV+ neurons almost never co-express ERα or AR, only the counts concerning relationships of PV+ neurons with ERβ were statistically evaluated by the two-tailed t test (* p ≤ 0.05, ** p ≤ 0.01 and *** p ≤ 0.001)