Table 1.
Summary of the effects of nLOT and sham lesions on body weights, fat mass, leptin and testosterone levels
| Control | Sham | nLOT lesion | |
|---|---|---|---|
| Body weight (g) | |||
| Day of surgery | 375 (4) | 361 (4) | 361 (6) |
| End of experiment | 435 (4)* | 401 (5)* | 404 (8)* |
| Fat mass (% bw) | 4.1 (0.1) | 2.9 (0.1)# | 3.2 (0.1)# |
| Leptin (ng/mL) | 5.3 (0.09) | 4.3 (0.09)# | 4.4 (0.06)# |
| Testosterone (ng/mL) | 2.1 (0.28) | 1.9 (0.26) | 2.5 (0.23) |
Values are expressed as mean (SEM)
* p < 0.001 compared with initial body weight of the respective group
# p < 0.001 compared with control rats