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. 2017 Oct 12;114(44):E9308–E9317. doi: 10.1073/pnas.1713625114

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Fig. S1. — Gene ontology (GO) term analysis, Wdr47 genotyping strategy, and LacZ profiling. (A) Gene enrichment analysis of molecular function for 286 hand-curated WDR murine genes vs. 26 WDR genes analyzed in this study. x Axis shows the negative logarithm (with base 10) of the P value, and y axis represents the GO term. (B) Allelic construction of KO mouse models and genotyping strategy; tm1a refers to the KO-first allele, and tm1a crossed with ROSA Cre deleter produces tm1b (complete KO). The illustration locates the seven primers designed to specifically target each component of the construction. Expected amplicon size is shown below each primer pair. A PCR example of the primer combinations used to genotypes Wdr47^tm1a and Wdr47^tm1b mice is shown in Lower Right. (C) Adult mice LacZ expression patterns across a selection of six tissues (brain, pancreas, bladder, lung, intestine, and spleen) accessible through the International Mouse Phenotyping Consortium (www.mousephenotype.org/data/genes/MGI:2139593) website.