Comparison between male and female Wdr47 mice using sagittal sections. (A) Correlation between phenotypic severity in fornix (f), anterior commissure anterior part (aca), and corpus callosum (cc) and percentage relative expression in both male and female. (B) Heat map of the effect size of the 95 neuroanatomical phenotypes (Dataset S8) quantified on three selected sagittal sections in three KO models (n = 3, male, female); nd refers to no data. 4V, fourth ventricle; 7N, facial nucleus; aca, anterior part of anterior commissure; acp, posterior part of anterior commissure; AD, anterodorsal thalamic nucleus; B, bottom; cc, corpus callosum; Cg, cingulate cortex; Cpu, caudate putamen; DG, dentate gyrus; DS, dorsal subiculum; f, fornix; fi, fimbria; Folia, number of folia; fp, fibre of pons; Gn, geniculate nucleus; GP, globus pallidus; hif, hippocampal fissure; HP, hippocampus; ic, internal capsule; IGL, internal granular layer of cerebellum; InfC, inferior colliculus; Lat, lateral cerebellar nucleus; LR4V, fourth ventricle; LSV, ventral part of lateral septal nucleus; LV, lateral ventricle; M1, primary motor cortex; M2, secondary motor cortex; Med, medial cerebellar nucleus; Mn, mammilary nucleus; Mol, molecular layer of HP; och, optic chiasm; opt, optic tract; Or, oriens layer of HP; Pir, piriform cortex; Pn, pontine nuclei; Rad, radiatum layer of HP; S1, primary somatosensory cortex; sm, stria medullaris; SN substantia nigra; SNR, substantia nigra region; T, top; TB_Height1, height at Bregma +0.86 mm; TB_Height2, height at Bregma −1.34 mm; TB_Width, width of the total brain; TBA, total brain area; TCA, total cerebellar area; TILpy, total internal length of pyramidal cell layer of HP; TOL, total outer length.