Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 6;149(11):985–1007. doi: 10.1085/jgp.201711845

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Zhou et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 6. — The RCK1 Ca²⁺-binding sites. (A) High-resolution view of the metal-free structure surrounding the RCK1 Ca²⁺-binding sites with coordinating residues labeled. Structures in A and B were aligned by the RCK2 αS helix that resides in the vicinity of the RCK1 binding site, but appears to undergo no major change between structures. (B) High-resolution view of the liganded aSlo1 structure surrounding the RCK1 binding site with coordination mediated by backbone carbonyls of aR503 (mR514), aG523 (mS533), and aE591 (mS600) and side chains of aD356 (mD367) and aE525 (mE535). Electrostatic interaction between aE912/aY914 near the Ca²⁺ bowl of the same subunit with the side chain of aR503 is proposed to underlie potential interactions between RCK1 and Ca²⁺ bowl binding sites.