Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 6;149(11):1009–1028. doi: 10.1085/jgp.201711827

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 Meyer et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 6. — Ouabain-sensitive currents in wild-type and mutant human Na/K pumps. (A–E) Mean ouabain-sensitive I-V plots in different ionic conditions from oocytes expressing wild-type (n = 5; A), L104R (n = 5; B), V332G (n = 5; C), delF100-L104 (n = 5; D), and EETA963S (n = 4; E) pumps, recorded 2–4 d after injection in experiments similar to those in Figs. 4 and 5. Shown are ouabain-sensitive currents in NMG⁺_o (circles), NMG⁺_o + 3 mM K⁺_o (up triangles), Na⁺_o (squares), and Na⁺_o + 4.5 mM K⁺_o (down triangles; symbol key in A). The insets in B–D show a zoomed-in view of the axes to illustrate the shift in reversal potential (V_REV) when Na⁺_o was replaced with NMG⁺_o. (F) Mean reversal potential of ouabain-sensitive currents in NMG⁺_o (solid bars) and Na⁺_o (striped bars). Error bars represent SEM.