Table 2.
Plasmodium falciparum samples with pfhrp2 or pfhrp3 deletion. Nine samples positive by three independent PCR assays, two of which target single-copy genes, were negative by PCR for pfhrp2 or pfhrp3. PCR outcome of the corresponding flanking regions are also shown. *Positive by qPCR with parasitaemia of 167 parasites per µL. Pfhrp2 and pfhrp3, Plasmodium falciparum histidine-rich protein 2 and 3 respectively; RDT, rapid diagnostic test; PF3D7_0831900 and PF3D7_0831700, upstream and downstream flanking regions of pfhrp2, PF3D7_1372100 and PF3D7_1372400, upstream and downstream flanking regions of pfhrp3.
Isolate | RDT | Parasitaemia | PF3D7_0831900 | pfhrp2 | PF3D7_0831700 | PF3D7_1372100 | pfhrp3 | PF3D7_1372400 |
---|---|---|---|---|---|---|---|---|
K165 | + | 3560 | − | − | + | + | + | + |
K027 | + | 240 | − | − | − | + | + | + |
K065 | + | 1720 | − | − | − | + | + | + |
K031 | + | 2400 | − | − | − | + | + | + |
K063 | + | 2120 | − | − | − | + | + | + |
K233 | + | 840 | − | − | − | + | + | + |
K263 | + | 480 | − | − | − | + | + | + |
K320 | + | 960 | − | − | + | + | + | + |
K182 | − | 0* | + | + | + | − | − | + |