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1.

Clinical characteristics of patients and univariate analysis of prognostic factors

Characteristics n 5-year LRFS (%) P 5-year MMFS (%) P 5-year PFS (%) P 5-year OS (%) P
LRFS, local progression-free survival; MMFS, multiple myeloma-free survival; PFS, progression-free survival; OS, overall survival; NA, not available; MM, multiple myeloma; RT, radiotherapy; CT, chemotherapy.
All patients 55 79.8 78.6 65.2 76.0
Age (year)
 ≥50 29 82.1 0.654 68.9 0.028 63.1 0.630 75.1 0.267
 <50 26 77.2 91.7 67.9 76.6
Gender
 Male 37 76.5 0.575 83.9 0.201 68.6 0.521 77.6 0.261
 Female 18 86.7 68.2 58.4 72.8
Sites
 Head and neck 39 91.8 0.004 89.6 0.003 75.9 0.026 77.4 0.625
 Others 16 49.0 48.5 34.5 72.9
Tumor size (cm)
 ≥4 20 80.0 0.761 56.1 0.013 44.5 0.022 46.2 0.044
 <4 35 79.5 88.1 75.0 89.0
Serum M protein
 Positive 26 75.2 0.113 78.9 0.033 57.1 0.030 66.3 0.229
 Negative 18 94.4 100 87.7 94.4
 NA 11 64.0 45.7 41.1 59.3
Progression to MM
 Present 10 45.7 0.021
 Absent 45 87.4
Local recurrence
 Present 12 48.9 0.001 56.8 0.358
 Absent 43 88.5 84.1
RT
 Yes 32 89.1 0.036 87.4 0.044 81.1 0.006 87.0 0.012
 No 23 60.4 61.2 37.2 53.8
Surgery
 Yes 29 80.2 0.320 74.8 0.102 55.1 0.055 81.0 0.620
 No 26 80.4 82.9 75.7 73.0
CT
 Yes 23 77.9 0.572 71.7 0.274 65.2 0.663 61.7 0.133
 No 32 81.1 82.7 65.9 81.0