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. 2017 Oct 3;7(11):3775–3787. doi: 10.1534/g3.117.300262

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Copyright © 2017 Omer et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(A) An example for an insertion mediated by a direct repeat. The top sequence in this pairwise alignment includes an insertion of 51 bp compared to the other strains (represented here by a single strain MD1020). The bottom sequence represents the ancestral form with the structure of ABA, and the top sequence with the insertion has the structure of ABABA (SGD position 470,500 on chrXIII). (B) Three types of changes at ChrII:392888 that were observed in rad27Δ strains. A unit of 16 bp composed of an 8-bp direct repeat (indicated as A) and an 8-bp unique sequence (indicated as B). Most strains, as well as the two zero and two five-strains, included the ancestral form of three copies of AB (represented here by strain MD1021). However, two independent strains (MD1020, MD1028) included four copies of AB, and one strain (MD1029) included two copies of AB. S. cerevisiae strain JAY291 has one AB unit, and YJM789 contained three AB units in this locus.