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. 2017 Sep 25;7(11):3797–3808. doi: 10.1534/g3.117.300224

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Copyright © 2017 Azadmanesh et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Gene upregulation is not linked to phenotypic defects in coordinate conditions. The expression of genes represented in the mutant collection were compared to the mutant phenotype of the respective deletion strain in each condition. For each condition, the number of strains with a severe phenotypic defect and upregulation of the respective gene were compared to the total number of strains exhibiting a defect in that condition to calculate the percentage defective in upregulated genes (dark gray bars). This is compared to the percentage of strains showing a phenotypic defect in each condition (light gray bars).