Table 2. Average filamentation scores and virulence.

Statea	Virulenceb	FBS	Lee’s	RPMI	Spider	YPD
Liquid	Defect	3.06	2.66c	3.12	2.89	3.39
Liquid	WT	3.35	1.74c	2.96	3.12	3.53
Solid	Defect	2.70	1.49c	2.25c	2.62	3.50
Solid	WT	2.81	2.08c	3.31c	2.56	3.57

^aState refers to liquid or solid assays.

^bVirulence refers to murine tail vein injection models of systemic infection. Values in each condition in the “defect” category represent the average filamentation score of strains with a competitive growth defect in a pooled experiment, a virulence defect in a single-strain assay with an analogous mutation in a different strain background, or in both. Values in the “WT” category represent average filamentation scores of strains with no known virulence defects. Note that most mutations in the WT strain set have not been tested in single-strain virulence assays.

^cP-value between strains grown in Lee’s liquid conditions is 6.3 × 10⁻⁶, in Lee’s solid conditions is 0.028, and between RPMI solid conditions is 6.5 × 10⁻⁶, as measured by a Students t-test.