Figure 1.

Global transcriptional response of C. albicans to carbon source, WOAs, and MIG1 inactivation. The figure displays a two-way hierarchical clustering of 6218 transcripts (rows) and 48 samples (columns). Log10-transformed RPKM expression values were converted to z-scores, with red indicating expression levels above and blue symbolizing expression levels below the mean expression level of each gene across the samples. Distance metric = 1 − Pearson correlation. RPKM, reads per kilobase per million mapped reads; WOAs, weak organic acids; YPD, yeast extract-peptone-dextrose media; YPM, media with identical composition to YPD except d-glucose replaced by maltose.