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. 2017 Sep 6;7(11):3597–3604. doi: 10.1534/g3.117.300238

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Copyright © 2017 Cottier et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Significantly regulated genes in response to different growth conditions. (A) Genes significantly regulated in response to glucose and maltose. Up- and downregulated genes obtained by comparison of transcriptional profiles between YPM over YPD media for SC3514 and mig1Δ strains. (B) Genes significantly regulated in response to WOAs. Up- and downregulated genes obtained by comparison of transcriptional profiles between YPD supplemented with acetic or butyric acid over YPD media for SC3514 strain. Not represented: one gene (orf19.3684) displayed opposite regulation between acetic acid (downregulation) and butyric acid (upregulation), and one with the opposite trend (orf19.7042). (C) Genes significantly regulated in MIG1 mutant. Up- and downregulated genes obtained by comparison of transcriptional profiles between mig1Δ over the SC3514 strain in YPD and YPM media. (D) Genes significantly regulated in response to carbon source in presence of WOAs. Up- and downregulated genes obtained by comparison of transcriptional profiles between YPM supplemented with acetic or butyric acid over YPD media supplemented with identical acids for the SC3514 strain. Not represented: nine genes displayed opposite regulation between acetic acid (downregulation) and butyric acid (upregulation). WOAs, weak organic acids; YPD, yeast extract-peptone-dextrose media; YPM, media with identical composition to YPD except d-glucose replaced by maltose.