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. 2017 Nov 2;9:551–557. doi: 10.2147/BCTT.S149752

Table 1.

General recommendations

General advice
• Skin cleansing
 ◦ Liquid soap or dermatological soap bar with a pH close to 5, without perfume, plant or fruit extracts
 ◦ Dry skin delicately but meticulously
• Skin hydration
 ◦ Apply a non-comedogenic emollient cream without perfume, lanoline, 1 or 2 times per day, preferably after the radiotherapy session
 ◦ Avoid applying topical creams to the radiation zone at least 1 hour before the radiotherapy session. This will avoid a bolus effect (increased radiation dose delivered to the epidermis)
• Photoprotection
 ◦ Protect the irradiated skin zone from sun exposure
 ◦ Apply a sunscreen SPF 50+ with UVA/UVB protection.
• Clothing
 ◦ Wear ample, soft cotton clothing
 ◦ Avoid wearing synthetic clothes
• Additional advice
 ◦ Use an electric razor and do not shave too close to the skin.
 ◦ Avoid applying products that contain alcohol (perfume, eau de toilette, ether, talcum powder)
 ◦ Avoid applying sticky plaster
 ◦ Avoid rubbing or scratching

Acute radiodermatitis

Grade 1
Mild to moderate erythema
Desquamation dry and moderately sensitive
graphic file with name bctt-9-551Fig3.jpg • Follow local hygiene routine
If needed:
• Emollient cream
• Topical corticotherapy
• Protective hydrogel, hydrobalance hydrocellular dressing
• Avoid “Tulle gras” dressing
• Low-energy laser (currently under evaluation)
Grade 2
Intense sensitive and mildly painful erythema
Moist lesions confined to skin folds
Edema
graphic file with name bctt-9-551Fig4.jpg • Continue local hygiene routine
If needed:
• Emollient cream
• Healing cream, acid hyaluronic cream
• Topical corticosteroid
• Drying lotion
• Absorbent, nonadhesive, protective dressing (hydrogel, hydrocellular, hydrobalance)
• Expose to fresh air as much as possible
• Avoid antibacterial application
• Low-energy laser (currently under evaluation)
Grade 3
Intense, painful erythema
Extensive weeping moist zones larger than skin fold areas
Bleeding wounds
graphic file with name bctt-9-551Fig5.jpg If needed:
Clean the wound with physiological serum
• Tulle gras dressing 1 or 2 times a day
• Nonadhesive, absorbent dressings, hydroabsorbant, hydrocellular
• Alginate dressing if bleeding
• Hydrofiber dressing if abundant exudate
After radiotherapy
• Continue using nonirritant local skin care, emollient, and sunscreen
• Avoid wearing constricting clothing, synthetic fabric for several weeks
• Watch daily for life

Notes: Data from these studies.16,42,43