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Mean annual total and severe exacerbation rates during follow-up. (Rates are calculated as the sum of exacerbations over all patients divided by the sum of follow-up time to correct for patients with a short follow-up time.)
Abbreviations: ECLIPSE, Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints; OLIN, Obstructive Lung Disease in Norrbotten.
