Table 3.
Relationship Between Fetal Thyroid Hypertrophy and Maternal TRAb Level
| Maternal MaxTRAb | Optimal Cutoff, IU/L | Sensitivity, % | Specificity,% | PPV, % | NPV, % | Correctly Classified, % | AUC |
|---|---|---|---|---|---|---|---|
| All women (n = 417) | 2.5 | 100 (100–100) | 64 (60–68) | 26 (22–30) | 100 (100–100) | 68 | 0.91 (0.87–0.94) |
| Receiving ATDs during pregnancy | |||||||
| Yes (n = 145; 35.0%) | 2.5 | 100 (100–100) | 39 (31–47) | 38 (30–46) | 100 (100–100) | 40 | 0.83 (0.76–0.90) |
| No (n = 272; 65.0%) | 2.5 | 100 (100–100) | 73 (68–78) | 8 (5–11) | 100 (100–100) | 74 | 0.91 (0.87–0.94) |
Data in parentheses are 95% confidence intervals.
Abbreviation: MaxTRAb, maximum TRAb.